Article
The activator of GntII genes for gluconate metabolism, GntH, exerts negative control of GntR-regulated GntI genes in Escherichia coli.
Journal of bacteriology - 1 Mar 2003
Tsunedomi Ryouichi, Izu Hanae, Kawai Takuya, Matsushita Kazunobu, Ferenci Thomas, Yamada Mamoru
Abstract excerpt
Gluconate is one of the preferred carbon sources of Escherichia coli, and two sets of gnt genes (encoding the GntI and GntII systems) are involved in its transport and metabolism. GntR represses the GntI genes gntKU and gntT, whereas GntH was previously suggested to be an activator for the GntII genes gntV and idnDO-gntWH. The helix-turn-helix residues of the two regulators GntR and GntH exhibit extensive...
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