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Article

The mouse as a developmental model for cleft lip and palate research.

Frontiers of oral biology - 1 Jan 2012

Gritli-Linde Amel

Abstract excerpt

Vertebrate and invertebrate model organisms are essential for deciphering biological processes. One of these, the mouse, proved to be a valuable model for understanding the etiopathogenesis of a vast array of human diseases, including congenital malformations such as orofacial clefting conditions. This small mammal's usefulness in cleft lip and palate research stems not only from the striking anatomical and...

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PMID: 22759668
DOI: 10.1159/000337523

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