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Article

Detection of monoclonality in low‐grade B‐cell lymphomas using the polymerase chain reaction is dependent on primer selection and lymphoma type

1 Mar 1993

Abstract excerpt

Detection of B-cell monoclonality using the polymerase chain reaction (PCR) promises the quick and cost-effective separation of monoclonal from polyclonal B-cell disease. However, the efficiency of the method has yet to be fully assessed, particularly with regard to disease type and selection of PCR primers. We have evaluated two approaches based on amplification of the immunoglobulin heavy chain gene using...

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PMID: 8492220
DOI: 10.1002/path.1711690303

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Source receipt: pubmed, retrieved 7 Sept 2026.

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