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Article

Sequence variation in the env gene of simian immunodeficiency virus recovered from immunized macaques is predominantly in the V1 region.

The Journal of general virology - 1 May 1993

Almond N, Jenkins A, Heath A B, Kitchin P

Abstract excerpt

Three cynomolgus macaques were immunized with recombinant envelope protein preparations derived from simian immunodeficiency virus (SIV). Although humoral and cellular responses were elicited by the immunization regime, all macaques became infected upon challenge with 10 MID50 of the 11/88 virus challenge stock of SIVmac251-32H. The polymerase chain reaction was used to amplify proviral SIV gp120 sequences...

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Identifiers

PMID: 8492090
DOI: 10.1099/0022-1317-74-5-865

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Sequence variation in the env gene of simian immunodeficiency virus recovered from immunized macaques is predominantly in the V1 region.PMID 8492090Read ↗

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