Subclustering of human immunoglobulin kappa light chain variable region genes.

doi:10.1006/geno.1993.1142

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Article

Subclustering of human immunoglobulin kappa light chain variable region genes.

Genomics - 1 Apr 1993

Kurth J H, Mountain J L, Cavalli-Sforza L L

Abstract excerpt

The human immunoglobulin kappa light chain (IgK) locus includes multiple variable region gene segments (Vk) that can be divided into four subgroups. Oligonucleotide primers were designed to amplify specifically gene segments of the VkI, VkII, and VkIII subgroups using the polymerase chain reactio...

Topics

Base Sequence
Biological Evolution
Conserved Sequence
DNA
DNA Probes
Genes, Immunoglobulin
Humans
Immunoglobulin Variable Region
Immunoglobulin kappa-Chains
Molecular Sequence Data
Multigene Family
Mutation
Polymerase Chain Reaction

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