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Article

Subclustering of human immunoglobulin kappa light chain variable region genes.

Genomics - 1 Apr 1993

Kurth J H, Mountain J L, Cavalli-Sforza L L

Abstract excerpt

The human immunoglobulin kappa light chain (IgK) locus includes multiple variable region gene segments (Vk) that can be divided into four subgroups. Oligonucleotide primers were designed to amplify specifically gene segments of the VkI, VkII, and VkIII subgroups using the polymerase chain reaction (PCR). Product sequences were subcloned, sequenced, and compared. Phylogenetic analyses of sequences within each...

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Identifiers

PMID: 8486386
DOI: 10.1006/geno.1993.1142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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