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Article

Reactive astrocytes in the kainic acid-damage hippocampus have the phenotypic features of type-2 astrocytes.

Journal of neurocytology - 1 Apr 1993

Represa A, Niquet J, Charriaut-Marlangue C, Ben-Ari Y

Abstract excerpt

Kainic acid treatment, a model of temporal lobe epilepsy, induces Ammon's horn sclerosis characterized by degeneration of CA3 pyramidal neurons and reactive gliosis. We now report that in kainic acid treated rats, reactive astrocytes in the hippocampus are A2B5 immunopositive and express GAP-43 immunoreactivity. A2B5 is a cell surface ganglioside selectively expressed in the glial O-2A lineage (oligodendrocytes...

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Source

Identifiers

PMID: 8478647
DOI: 10.1007/BF01187128

Genes

GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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