Article
Transactivation of cellular promoters by an integrated hepatitis B virus DNA.
Biochemical and biophysical research communications - 15 Apr 1993
Yamamoto S, Nakatake H, Kawamoto S, Takimoto M, Koshy R, Matsubara K
Abstract excerpt
A new Hepatitis B virus(HBV) DNA integrant clone DA2-6, isolated from a human hepatocellular carcinoma(HCC) genomic library, was tested for its ability to transactivate expression of other genes. DA2-6 consists of 3.7 kb flanking cellular sequences and an integrated 2.8 kb HBV DNA which covers th...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA, Viral
- Hepatitis B virus
- Humans
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Terminator Regions, Genetic
- Trans-Activators
- Transcription, Genetic
- Transcriptional Activation
- Tumor Cells, Cultured
- Viral Regulatory and Accessory Proteins
- Virus Integration