Article
Pathogenicity Island Cross Talk Mediated by Recombination Directionality Factors Facilitates Excision from the Chromosome.
Journal of bacteriology - 14 Dec 2015
Carpenter Megan R, Rozovsky Sharon, Boyd E Fidelma
Abstract excerpt
UNLABELLED: Pathogenicity islands (PAIs) are mobile integrated genetic elements (MIGEs) that contain a diverse range of virulence factors and are essential in the evolution of pathogenic bacteria. PAIs are widespread among bacteria and integrate into the host genome, commonly at a tRNA locus, via integrase-mediated site-specific recombination. The excision of PAIs is the first step in the horizontal transfer of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
