Article
The vibrio pathogenicity island of epidemic Vibrio cholerae forms precise extrachromosomal circular excision products.
Journal of bacteriology - 1 Dec 2003
Rajanna C, Wang J, Zhang D, Xu Zheng, Ali A, Hou Y-M, Karaolis D K R
Abstract excerpt
The Vibrio pathogenicity island (VPI) in epidemic Vibrio cholerae is an essential virulence gene cluster. Like many pathogenicity islands, the VPI has at its termini a phage-like integrase gene (int), a transposase-like gene (vpiT), and phage-like attachment (att) sites, and is inserted at a tRNA-like locus (ssrA). We report that the VPI precisely excises from the chromosome and that its left and right ends join...
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