Article
Phospholipase A2 in alveolar type II epithelial cells: biochemical and immunologic characterization.
The American journal of physiology - 1 Mar 1993
Neagos G R, Feyssa A, Peters-Golden M
Abstract excerpt
The enzyme phospholipase A2 (PLA2) catalyzes phospholipid hydrolysis and is thought to play important roles in surfactant synthesis and in the generation of lipid mediators, including eicosanoids and platelet-activating factor. This study sought to characterize PLA2 in rat type II pneumocytes by...
Topics
- Animals
- Calcium
- Cells, Cultured
- Cytosol
- Dithiothreitol
- Dose-Response Relationship, Drug
- Electrophoresis, Polyacrylamide Gel
- Epithelial Cells
- Epithelium
- Humans
- Immunoblotting
- Lung Neoplasms
- Male
- Phenotype
- Phospholipases A
- Phospholipases A2
- Pulmonary Alveoli
- Rats