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Article

Development of immortalized human articular cartilage cell lines.

Agents and actions. Supplements - 1 Jan 1993

Verbruggen G, Malfait A M, Almqvist K F, Veys E M, Thenet S, Benoit B, Demignot S, Tachet des Combes A, Adolphe M

Abstract excerpt

Human articular cartilage cells were transfected with the t.-sensitive polyomavirus large T antigen of SV40. Several immortalized chondrocyte cell lines were obtained. The types of acidic polysaccharides and of collagen synthesized suggest dedifferentiation in the in vitro culture system used afterwards to obtain large numbers of cells.

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Share to Antigens, Polyomavirus Transforming
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8456640
DOI: 10.1007/978-3-0348-7442-7_33

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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