Article
Difference in HLA-linked genetic background between mixed connective tissue disease and systemic lupus erythematosus.
Tissue antigens - 1 Jan 1993
Dong R P, Kimura A, Hashimoto H, Akizuki M, Nishimura Y, Sasazuki T
Abstract excerpt
We have typed 64 Japanese patients with mixed connective tissue disease (MCTD) and 53 Japanese patients with systemic lupus erythematosus (SLE) for HLA-DRB1, DRB3, DRB4, DRB5, DQA1, DQB1, and DPB1 genes by the HLA-DNA typing method using the PCR-SSOP technique. Frequencies of HLA-DRB1*0401, DRB1*...
Topics
- Alleles
- Autoimmune Diseases
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-D Antigens
- Haplotypes
- Histocompatibility Testing
- Humans
- Japan
- Lupus Erythematosus, Systemic
- Mixed Connective Tissue Disease