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Prolactin Supplementation to Culture Medium Improves β-Cell Survival

30 Mar 2010

Abstract excerpt

OBJECTIVES: Recent studies demonstrated that prolactin (PRL) has beneficial effects on beta cells for islet transplantation. We examined the effect of human recombinant PRL (rhPRL) supplementation to the culture media to determine its potential use in the context of clinical islet transplantation. MATERIALS AND METHODS: Each human islet isolated from 14 deceased multiorgan donors was cultured in Miami modified...

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PMID: 20357700
DOI: 10.1097/tp.0b013e3181d98af1

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