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Article

Overexpression of alpha1beta1 integrin directly affects rat mesangial cell behavior.

Kidney international - 1 Sept 2000

Kagami S, Kondo S, Urushihara M, Löster K, Reutter W, Saijo T, Kitamura A, Kobayashi S, Kuroda Y

Abstract excerpt

BACKGROUND: Glomerular mesangial cell (MC) proliferation, hypertrophy, and abnormal matrix remodeling characterized by increased expression of fibronectin, laminin and collagen type IV, and neoexpression of collagen I and III are the main biological features of progressive glomerulonephritis (GN). Especially, persistent pathological matrix remodeling may lead to glomerular scar formation (glomerular scarring). We...

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Identifiers

PMID: 10972673
DOI: 10.1046/j.1523-1755.2000.00266.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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