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Article

Circulating HIV-specific CD8+ cytotoxic T cells express CD38 and HLA-DR antigens

1 Apr 1993

Abstract excerpt

CD38, a molecule with multilineage distribution but unknown function, and the MHC class II molecule HLA-DR (DR) have markedly elevated levels of expression on CD8+ cells of HIV-infected people. This study investigated the expression of CD38 and DR Ag on circulating HIV-specific CD8+ CTL in HIV-seropositive subjects. Purified CD8+ lymphocytes from 22 participants in the University of California at Los Angeles...

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PMID: 8454874
DOI: 10.4049/jimmunol.150.7.3070

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