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Article

Association of HLA Genotype With T-Cell Activation in Human Immunodeficiency Virus (HIV) and HIV/Hepatitis C Virus-Coinfected Women.

The Journal of infectious diseases - 16 Mar 2020

Kovacs Andrea A Z, Kono Naoko, Wang Chia-Hao, Wang Daidong, Frederick Toni, Operskalski Eva, Tien Phyllis C, French Audrey L, Minkoff Howard, Kassaye Seble, T Golub Elizabeth, Aouizerat Bradley E, Kuniholm Mark H, Millstein Joshua

Abstract excerpt

BACKGROUND: Global immune activation and HLA alleles are each associated with the pathogenesis of human immunodeficiency virus (HIV) and hepatitis C virus . METHODS: We evaluated the relationship between 44 HLA class I and 28 class II alleles and percentages of activated CD8 (CD8+CD38+DR+) and CD4 (CD4+CD38+DR+) T cells in 586 women who were naive to highly active antiretroviral therapy. We used linear...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31802115
DOI: 10.1093/infdis/jiz589
PMCID: PMC7325713

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