Article
Subset markers of CD8(+) cells and their relation to enhanced cytotoxic T-cell activity during human immunodeficiency virus infection.
Journal of clinical immunology - 1 Nov 1991
Vanham G, Kestens L, Penne G, Goilav C, Gigase P, Colebunders R, Vandenbruaene M, Goeman J, van der Groen G, Ceuppens J L
Abstract excerpt
Using fresh whole blood or isolated lymphocytes, the activity of in vivo generated cytotoxic T-lymphocytes (CTL) was measured as the OKT3-specific lysis of HL-60 targets, in a cross-sectional study of 53 HIV (+) patients. CTL activity in the entire HIV(+) group was two to three times higher than...
Topics
- ADP-ribosyl Cyclase
- ADP-ribosyl Cyclase 1
- Antigens, CD
- Antigens, Differentiation
- CD8 Antigens
- Cytotoxicity, Immunologic
- Female
- HIV Infections
- Humans
- Male
- Membrane Glycoproteins
- Muromonab-CD3
- Phenotype
- T-Lymphocyte Subsets
- T-Lymphocytes, Cytotoxic