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Article

D21S210: a highly polymorphic (GT)n marker closely linked to the beta-amyloid protein precursor (APP) gene.

Human genetics - 1 Mar 1993

Warren A C, McInnis M G, Kalaitsidaki M, Cox T K, Blaschak J, Chakravarti A, Antonarakis S E

Abstract excerpt

We describe a highly polymorphic (GT)n repeat with 14 alleles that is closely linked to the amyloid precursor protein (APP) gene on human chromosome 21. This marker, D21S210, will be useful for studies of linkage of disorders such as Alzheimer disease to the APP gene.

Topics

Alleles
Amyloid beta-Protein Precursor
Base Sequence
Chromosomes, Human, Pair 21
Female
Gene Frequency
Genetic Linkage
Humans
Male
Molecular Sequence Data
Pedigree
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8454294
DOI: 10.1007/BF00230232

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8454294-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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