Article
Microsatellite D21S210 (GT-12) allele frequencies in sporadic Alzheimer's disease.
Acta neurologica Scandinavica - 1 Feb 1995
Lannfelt L, Lilius L, Viitanen M, Houlden H, Rossor M, Hardy J, Winblad B, Basun H
Abstract excerpt
Four disease-causing mutations have so far been described in the amyloid precursor protein gene on chromosome 21 in familial early-onset Alzheimer's disease. Linkage analysis with a fourteen-allele microsatellite at D21S210 named GT-12 has proven useful in the elucidation of amyloid precursor protein gene involvement in Alzheimer's disease families, as it is closely linked to the gene. Most cases of Alzheimer's...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.