Article
Microsatellite allele frequencies in humans and chimpanzees, with implications for constraints on allele size.
Molecular biology and evolution - 1 Jul 1995
Garza J C, Slatkin M, Freimer N B
Abstract excerpt
The distributions of allele sizes at eight simple-sequence repeat (SSR) or microsatellite loci in chimpanzees are found and compared with the distributions previously obtained from several human populations. At several loci, the differences in average allele size between chimpanzees and humans are sufficiently small that there might be a constraint on the evolution of average allele size. Furthermore, a model...
Topics
- Alleles
- Animals
- Base Sequence
- DNA Primers
- DNA, Satellite
- Genetic Variation
- Genetics, Population
- Humans
- Models, Genetic
- Molecular Sequence Data
- Mutagenesis
- Mutation