The number of alleles at a microsatellite defines the allele frequency spectrum and facilitates fast accurate estimation of theta.

Abstract excerpt

Theoretical work focused on microsatellite variation has produced a number of important results, including the expected distribution of repeat sizes and the expected squared difference in repeat size between two randomly selected samples. However, closed-form expressions for the sampling distribution and frequency spectrum of microsatellite variation have not been identified. Here, we use coalescent simulations...

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