Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A mutation in algN permits trans activation of alginate production by algT in Pseudomonas species.

Journal of bacteriology - 1 Mar 1993

Goldberg J B, Gorman W L, Flynn J L, Ohman D E

Abstract excerpt

Conversion of the mucoid phenotype, which results from the production of the exopolysaccharide alginate, is a feature typical of Pseudomonas aeruginosa strains causing chronic pulmonary infections in patients with cystic fibrosis. In this study, we further characterized a recombinant plasmid, called pJF15, that contains DNA from the 65- to 70-min region of the chromosome of mucoid P. aeruginosa FRD1 and has loci...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacterial Proteins
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Bacterial

Share to Genes, Bacterial

Share to Molecular Sequence Data

Share to Mutation

Share to Restriction Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 8444793
DOI: 10.1128/jb.175.5.1303-1308.1993
PMCID: PMC193215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A mutation in algN permits trans activation of alginate production by algT in Pseudomonas species.PMID 8444793Read ↗

Mucoid-to-nonmucoid conversion in alginate-producing Pseudomonas aeruginosa often results from spontaneous mutations in algT, encoding a putative alternate sigma factor, and shows evidence for autoregulation.Semantic proximity Read ↗

Sigma factor-anti-sigma factor interaction in alginate synthesis: inhibition of AlgT by MucA.Semantic proximity Read ↗

Deletion of algK in mucoid Pseudomonas aeruginosa blocks alginate polymer formation and results in uronic acid secretion.Semantic proximity Read ↗

Identification of algF in the alginate biosynthetic gene cluster of Pseudomonas aeruginosa which is required for alginate acetylation.Semantic proximity Read ↗

Differentiation of Pseudomonas aeruginosa into the alginate-producing form: inactivation of mucB causes conversion to mucoidy.Semantic proximity Read ↗

Transcriptional analysis of the Pseudomonas aeruginosa genes algR, algB, and algD reveals a hierarchy of alginate gene expression which is modulated by algT.Semantic proximity Read ↗

Genetic analysis of the alginate biosynthetic gene cluster of <i>Pseudomonas aeruginosa</i> shows evidence of an operonic structureSemantic proximity Read ↗

Identification of an Escherichia coli pepA homolog and its involvement in suppression of the algB phenotype in mucoid Pseudomonas aeruginosa.Semantic proximity Read ↗

Pseudomonas aeruginosa AlgB, which modulates the expression of alginate, is a member of the NtrC subclass of prokaryotic regulators.Semantic proximity Read ↗

The Alternative Sigma Factor AlgT RepressesPseudomonas aeruginosaFlagellum Biosynthesis by Inhibiting Expression offleQSemantic proximity Read ↗

Outer-membrane protein LptD (PA0595) plays a role in the regulation of alginate synthesis in Pseudomonas aeruginosa.Semantic proximity Read ↗

Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.