Article
Integration of multiple developmental signals in Bacillus subtilis through the Spo0A transcription factor.
Genes & development - 1 Feb 1993
Ireton K, Rudner D Z, Siranosian K J, Grossman A D
Abstract excerpt
Multiple physiological and environmental signals are needed to initiate endospore formation in Bacillus subtilis. One key event controlling sporulation is activation of the Spo0A transcription factor. Spo0A is a member of a large family of conserved regulatory proteins whose activity is controlled by phosphorylation. We have isolated deletion mutations that remove part of the conserved amino terminus of Spo0A and...
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