Article
Gene expression in single cells of Bacillus subtilis: evidence that a threshold mechanism controls the initiation of sporulation.
Journal of bacteriology - 1 Apr 1994
Chung J D, Stephanopoulos G, Ireton K, Grossman A D
Abstract excerpt
Early during endospore formation in the bacterium Bacillus subtilis, two distinct cell types are formed. The initiation of this developmental pathway requires several physiological conditions (e.g., nutrient deprivation) and is controlled by the Spo0A transcription factor. We have found that in a...
Topics
- Bacillus subtilis
- Bacterial Proteins
- Gene Expression Regulation, Bacterial
- Genetic Variation
- Lac Operon
- Morphogenesis
- Mutation
- Protein Kinases
- Recombinant Fusion Proteins
- Sigma Factor
- Spores, Bacterial
- Transcription Factors