Article
Multiple protein-aspartate phosphatases provide a mechanism for the integration of diverse signals in the control of development in B. subtilis.
Cell - 16 Dec 1994
Perego M, Hanstein C, Welsh K M, Djavakhishvili T, Glaser P, Hoch J A
Abstract excerpt
The initiation of sporulation in B. subtilis is regulated by the Spo0A transcription factor, which is activated by phosphorylation to control developmental switching from the vegetative to the sporulation state. The level of phosphorylation of Spo0A is regulated by the phosphorelay, a signal transduction system based on the protein-histidine kinase-response regulator two-component paradigm. To initiate...
Topics
- Amino Acid Sequence
- Bacillus subtilis
- Bacterial Proteins
- Cell Differentiation
- DNA-Binding Proteins
- Gene Expression Regulation, Bacterial
- Molecular Sequence Data
- Mutation
- Phosphoprotein Phosphatases
- Restriction Mapping