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Article

A genetic analysis of Spo0A structure and function.

Research in microbiology - 1 Jan 2000

Green B D, Olmedo G, Youngman P

Abstract excerpt

Mutations that enhanced sporulation in the presence of high concentrations of key nutrients (coi mutations) included at least four lesions within the phosphoacceptor domain of spo0A, a member of the response regulator family of "two-component" signal transduction proteins. The nature of these mutations and the phenotypes they produce support the model that the sporulation state of Spo0A controls the initiation of...

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Share to Bacillus subtilis
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 1664535
DOI: 10.1016/0923-2508(91)90061-e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A genetic analysis of Spo0A structure and function.PMID 1664535Read ↗

Novel mutations that alter the regulation of sporulation in Bacillus subtilis. Evidence that phosphorylation of regulatory protein SpoOA controls the initiation of sporulation.Semantic proximity Read ↗

Mutational dissociation of the positive and negative regulatory properties of the Spo0A sporulation transcription factor of Bacillus subtilis.Semantic proximity Read ↗

Integration of multiple developmental signals in Bacillus subtilis through the Spo0A transcription factor.Semantic proximity Read ↗

Mutational analysis of conserved residues in the putative DNA-binding domain of the response regulator Spo0A of Bacillus subtilis.Semantic proximity Read ↗

Molecular and phenotypic characterization of promoter-proximal mutations in the spoIIA locus of Bacillus subtilis.Semantic proximity Read ↗

Lessons and questions from the structure of the Spo0A activation domain.Semantic proximity Read ↗

Spo0A activates and represses its own synthesis by binding at its dual promoters.Semantic proximity Read ↗

The Spo0A sof mutations reveal regions of the regulatory domain that interact with a sensor kinase and RNA polymerase.Semantic proximity Read ↗

Suppressors of a spo0A missense mutation and their effects on sporulation in Bacillus subtilis.Semantic proximity Read ↗

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Mutation in yaaT leads to significant inhibition of phosphorelay during sporulation in Bacillus subtilis.Semantic proximity Read ↗

In vivo effects of sporulation kinases on mutant Spo0A proteins in Bacillus subtilis.Semantic proximity Read ↗

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