Article
A genetic analysis of Spo0A structure and function.
Research in microbiology - 1 Jan 2000
Green B D, Olmedo G, Youngman P
Abstract excerpt
Mutations that enhanced sporulation in the presence of high concentrations of key nutrients (coi mutations) included at least four lesions within the phosphoacceptor domain of spo0A, a member of the response regulator family of "two-component" signal transduction proteins. The nature of these mutations and the phenotypes they produce support the model that the sporulation state of Spo0A controls the initiation of...
Topics
- Bacillus subtilis
- Chromosome Deletion
- Gene Expression Regulation, Bacterial
- In Vitro Techniques
- Phenotype
- Phosphorylation
- Phosphotransferases
- Spores, Bacterial
- Suppression, Genetic
- Transduction, Genetic