Article
Genetic and molecular characterization of P element-induced mutations reveals that the Drosophila ovarian tumor gene has maternal activity and a variable null phenotype.
Genetics - 1 Feb 1993
Geyer P K, Patton J S, Rodesch C, Nagoshi R N
Abstract excerpt
The mutations in the ovarian tumor (otu) gene arrest oogenesis at several stages in development. A series of deletion mutations in the otu region were characterized, each of which causes the absence or reduction of the otu transcript. These alleles range from the most severe class, which results...
Topics
- Alleles
- Animals
- Base Sequence
- Crosses, Genetic
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Infertility, Female
- Insect Hormones
- Molecular Sequence Data
- Mutagenesis, Insertional
- Oncogenes
- Oogenesis
- Ovarian Cysts
- Ovarian Neoplasms
- Ovary
- Phenotype
- Sequence Deletion