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Article

The ovarian tumor protein isoforms of Drosophila melanogaster exhibit differences in function, expression, and localization.

Developmental biology - 1 Jan 1995

Sass G L, Comer A R, Searles L L

Abstract excerpt

The Drosophila melanogaster ovarian tumor (otu) gene, required for normal proliferation and differentiation of the female germ-line, encodes two cytoplasmic protein isoforms, 98 and 104 kDa. Mutants with defects in this gene are typically grouped into one of three phenotypic classes: quiescent (germ cells do not proliferate), oncogenic or tumorous (germ-line cells proliferate uncontrollably), and differentiated...

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Identifiers

PMID: 7851643
DOI: 10.1006/dbio.1995.1017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The ovarian tumor protein isoforms of Drosophila melanogaster exhibit differences in function, expression, and localization.PMID 7851643Read ↗

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Co-expressed Cyclin D variants cooperate to regulate proliferation of germline nuclei in a syncytium.Semantic proximity Read ↗

The Drosophila gene fs(2)cup interacts with otu to define a cytoplasmic pathway required for the structure and function of germ-line chromosomes.Semantic proximity Read ↗

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