Article
Structure and expression of hybrid dysgenesis-induced alleles of the ovarian tumor (otu) gene in Drosophila melanogaster.
Genetics - 1 Feb 1993
Sass G L, Mohler J D, Walsh R C, Kalfayan L J, Searles L L
Abstract excerpt
Mutations at the ovarian tumor (otu) gene of Drosophila melanogaster cause female sterility and generate a range of ovarian phenotypes. Quiescent (QUI) mutants exhibit reduced germ cell proliferation; in oncogenic (ONC) mutants germ cells undergo uncontrolled proliferation generating excessive nu...
Topics
- Alleles
- Animals
- Base Sequence
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Gene Expression Regulation
- Genes
- Hybridization, Genetic
- Infertility, Female
- Insect Hormones
- Molecular Sequence Data
- Mutagenesis, Insertional
- Oncogenes
- Oogenesis
- Ovarian Neoplasms
- Phenotype
- Sequence Deletion