Article
Genetic susceptibility to the induction of murine experimental autoimmune orchitis (EAO) without adjuvant. II. Analysis on susceptibility to EAO induction using F1 hybrid mice and adoptive transfer system.
Clinical immunology and immunopathology - 1 Mar 1993
Tokunaga Y, Hiramine C, Hojo K
Abstract excerpt
In our novel murine model of experimental autoimmune orchitis (EAO) induced by two or three injections of viable syngeneic testicular germ cells (TC) alone, significant differences in susceptibility to the induction of EAO were found, and the disease susceptibility did not seem to be associated with a particular H-2 haplotype. The H-2 identical background disparate (highly susceptible x low susceptible)F1...
Topics
- Animals
- Antibody Formation
- Autoimmune Diseases
- Genetic Predisposition to Disease
- Hybridization, Genetic
- Hypersensitivity, Delayed
- Immunization
- Immunotherapy, Adoptive
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred Strains
- Orchitis
- Spermatozoa