Article
F1 hybrid mice (BALB/c x DBA/1) are resistant to collagen-induced arthritis with beta-glucan as an adjuvant.
Biological & pharmaceutical bulletin - 1 Jun 2006
Hida Shunsuke, Nagi-Miura Noriko, Adachi Yoshiyuki, Ohno Naohito
Abstract excerpt
Collagen-induced arthritis (CIA) is an experimental model of rheumatoid arthritis (RA) used for studying the clinical, immunological and genetic factors of the disease. Many studies of genetic susceptibility to CIA have been performed, usually with two strains of mice, DBA/1 and B10.RIII, since they are highly susceptible to CIA. Furthermore, F1 hybrid mice of susceptible and resistant strains reportedly develop...
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