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Article

Inhibition of dysthrombins Quick I and II by heparin cofactor II and antithrombin.

The Journal of biological chemistry - 15 Feb 1993

Phillips J E, Shirk R A, Whinna H C, Henriksen R A, Church F C

Abstract excerpt

Heparin cofactor II and antithrombin are plasma serine proteinase inhibitors whose ability to inhibit alpha-thrombin is accelerated by glycosaminoglycans. Dysfunctional thrombin mutants Quick I (Arg67-->Cys) and Quick II (Gly226-->Val) were used to further compare heparin cofactor II and antithrombin interactions. Quick I, Quick II, and alpha-thrombin were eluted at the same salt concentration from...

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PMID: 8429008

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Inhibition of dysthrombins Quick I and II by heparin cofactor II and antithrombin.PMID 8429008Read ↗

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The preferred pathway of glycosaminoglycan-accelerated inactivation of thrombin by heparin cofactor II.Semantic proximity Read ↗

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