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Article

GATA1 mutations in red cell disorders.

IUBMB life - 1 Jan 2020

Ling Te, Crispino John D

Abstract excerpt

GATA1 is an essential regulator of erythroid cell gene expression and maturation. In its absence, erythroid progenitors are arrested in differentiation and undergo apoptosis. Much has been learned about GATA1 function through animal models, which include genetic knockouts as well as ones with decreased levels of expression. However, even greater insights have come from the finding that a number of rare red cell...

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Identifiers

PMID: 31652397
DOI: 10.1002/iub.2177
PMCID: PMC7323890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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