Article
Worldwide evaluation of DNA sequencing approaches for identification of drug resistance mutations in the human immunodeficiency virus type 1 reverse transcriptase.
Journal of clinical microbiology - 1 Jul 1999
Schuurman R, Demeter L, Reichelderfer P, Tijnagel J, de Groot T, Boucher C
Abstract excerpt
A panel (ENVA-1) of well-defined blinded samples containing wild-type and mutant human immunodeficiency virus type 1 (HIV-1) reverse transcriptase was analyzed by automated DNA sequencing in 23 laboratories worldwide. Drug resistance mutations at codons 41, 215, and 184 were present in the panel...
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