Article
ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2.
Molecular and cellular biology - 1 Oct 1993
Piña B, Berger S, Marcus G A, Silverman N, Agapite J, Guarente L
Abstract excerpt
We describe the isolation of a yeast gene, ADA3, mutations in which prevent the toxicity of GAL4-VP16 in vivo. Toxicity was previously proposed to be due to the trapping of general transcription factors required at RNA polymerase II promoters (S. L. Berger, B. Piña, N. Silverman, G. A. Marcus, J. Agapite, J. L. Regier, S. J. Triezenberg, and L. Guarente, Cell 70:251-265, 1992). trans activation by VP16 as well as...
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