Trans-specific Mhc polymorphism and the origin of species in primates.

Article

Trans-specific Mhc polymorphism and the origin of species in primates.

Journal of medical primatology - 1 Jan 1993

Klein J, Satta Y, Takahata N, O'hUigin C

Abstract excerpt

The major histocompatibility complex (Mhc) is a cluster of loci controlling the specific immune response in vertebrates. Mhc alleles often differ by a large number of nucleotide substitutions, some of which began to accumulate before the emergence of extant species. We have applied the theory of...

Topics

Alleles
Animals
Biological Evolution
Computer Simulation
Genetics, Population
Humans
Major Histocompatibility Complex
Models, Genetic
Pan troglodytes
Polymorphism, Genetic
Primates
Species Specificity

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