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Article

Long-term thymic reconstitution by peripheral CD4 and CD8 single-positive lymphocytes.

European journal of immunology - 1 Oct 1993

Hilbert D M, Holmes K L, Anderson A O, Rudikoff S

Abstract excerpt

Significant immigration of peripheral T cells into SCID thymus was observed following reconstitution with normal Peyer's patch, mesenteric lymph node or peripheral lymph node cells. Immunohistologic and flow cytometric analyses reveal that T cells from these tissues are found in the thymus for as long as 177 days and can account for up to 67% of intrathymic cells. The returning cells express the CD3/T cell...

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PMID: 8405041
DOI: 10.1002/eji.1830231006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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