Apolipoprotein(a) size heterogeneity is related to variable number of repeat sequences in its mRNA.

doi:10.1021/bi00455a007

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Article

Apolipoprotein(a) size heterogeneity is related to variable number of repeat sequences in its mRNA.

Biochemistry - 23 Jan 1990

Koschinsky M L, Beisiegel U, Henne-Bruns D, Eaton D L, Lawn R M

Abstract excerpt

Plasma apolipoprotein(a) [apo(a)] shows considerable size heterogeneity, existing as discrete glycoprotein isoform variants that range in apparent molecular mass from approximately 400 to 800 kDa. To study the molecular basis of protein size variability, we have isolated liver RNA from individual...

Topics

Apolipoproteins A
Base Sequence
Genetic Variation
Humans
Lipoprotein(a)
Lipoproteins
Molecular Structure
Molecular Weight
RNA, Messenger
Structure-Activity Relationship
Transcription, Genetic

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