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Article

Angiotensinogen gene and hypertension in Chinese.

The Journal of clinical investigation - 1 Jan 1998

Niu T, Xu X, Rogus J, Zhou Y, Chen C, Yang J, Fang Z, Schmitz C, Zhao J, Rao V S, Lindpaintner K

Abstract excerpt

The renin-angiotensin system plays a major role in regulating blood pressure and maintaining electrolyte and volume homeostasis. Previously, the angiotensinogen gene, which encodes the key substrate for renin within this system, has been reported linked to and associated with essential hypertension in White Europeans, African-Caribbeans, and Japanese. Therefore, we investigated whether the angiotensinogen gene...

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Identifiers

PMID: 9421481
DOI: 10.1172/JCI119876
PMCID: PMC508555

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