Article
Use of the novel INNO-LiPA line probe assay for detection of hepatitis B virus variants that confer resistance to entecavir therapy.
Journal of clinical microbiology - 1 Feb 2009
Jardi Rosendo, Rodriguez-Frias Francisco, Tabernero David, Homs Maria, Schaper Melanie, Esteban Rafael, Buti Maria
Abstract excerpt
A line probe assay (INNO-LiPA DR, version 3) for the detection of hepatitis B virus mutations that confer resistance to entecavir therapy was evaluated. The INNO-LiPA DR assay is a highly sensitive assay that is easily applicable for the detection and monitoring of entecavir resistance-conferring mutations and is more sensitive than sequencing for the detection of mixed sequences.
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