Article
Pathogenesis of lung cancer signalling pathways: roadmap for therapies.
The European respiratory journal - 1 Jun 2009
Brambilla E, Gazdar A
Abstract excerpt
Lung cancer is the major cancer killer worldwide, and 5-yr survival is extremely poor (<or=15%), accentuating the need for more effective therapeutic strategies. Significant advances in lung cancer biology may lead to customised therapy based on targeting specific genes and pathways. The main signalling pathways that could provide roadmaps for therapy include the following: growth promoting pathways (Epidermal...
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