Article
Molecular pathology of lung cancer.
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 2000
Wistuba I I, Gazdar A F
Abstract excerpt
Our understanding of the molecular pathology of lung cancer is advancing rapidly with several specific genes and chromosomal regions being identified. Lung cancer appears to require many mutations in both dominant and recessive oncogenes before they become invasive. Several genetic and epigenetic changes are common to all lung cancer histologic types, while others appear to be tumor type specific. The...
Topics
- Biomarkers, Tumor
- Cell Transformation, Neoplastic
- Chromosome Mapping
- Genetic Markers
- Humans
- Lung Neoplasms
- Mutation
- Oncogenes