Article
Oncogene rearrangement in non-Hodgkin's lymphoma with a 14q+ chromosome of unknown origin.
Leukemia & lymphoma - 1 May 1993
Nakamine H, Masih A S, Chan W C, Sanger W G, Armitage J O, Weisenburger D D
Abstract excerpt
Southern blot analysis was performed with a panel of DNA probes to detect rearrangements of c-myc, bcl-1, bcl-2 and bcl-3 in 14 cases of B-cell non-Hodgkin's lymphoma (NHL) with a clonal cytogenetic rearrangement involving the chromosome 14q32 locus and no known donor chromosome [t(14;?)(q32;?)]. In our experience, 21% of all chromosomal abnormalities involving the 14q32 locus in B-cell NHL are of this type. We...
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