Article
Insulin and islet cell autoantibodies as time-dependent covariates in the development of insulin-dependent diabetes: a prospective study in relatives.
The Journal of clinical endocrinology and metabolism - 1 Sept 1993
Krischer J P, Schatz D, Riley W J, Spillar R P, Silverstein J H, Schwartz S, Malone J, Shah S, Vadheim C M, Rotter J I
Abstract excerpt
Using time-dependent methods, the temporal relationships between the detection of insulin and islet cell autoantibodies and the onset of insulin dependent diabetes (IDDM) were analyzed in a prospective study of 4694 nondiabetic relatives of 1929 patients with IDDM who had been followed for a medi...
Topics
- Adolescent
- Adult
- Autoantibodies
- Blood Glucose
- Child
- Diabetes Mellitus, Type 1
- Fasting
- Glucose Tolerance Test
- HLA-DR Antigens
- Humans
- Insulin Antibodies
- Phenotype
- Prospective Studies
- Risk Factors