Article
Soluble CD4 and CD4 immunoglobulin-selected HIV-1 variants: a phenotypic characterization.
AIDS research and human retroviruses - 1 Jul 1993
Klasse P J, McKeating J A
Abstract excerpt
The selection of HIV-1 resistance to neutralization by both monovalent and bivalent forms of soluble CD4 was demonstrated under various conditions. Phenotypic traits of the neutralization-resistant variants were systematically explored in order to gain insight into which aspects of the interactions with CD4 are most expendable to HIV-1 replication. The size of the nonneutralized fraction after treatment of...
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