Article
Soluble CD4 and CD4 immunoglobulin-selected HIV-1 variants: a phenotypic characterization.
AIDS research and human retroviruses - 1 Jul 1993
Klasse P J, McKeating J A
Abstract excerpt
The selection of HIV-1 resistance to neutralization by both monovalent and bivalent forms of soluble CD4 was demonstrated under various conditions. Phenotypic traits of the neutralization-resistant variants were systematically explored in order to gain insight into which aspects of the interactio...
Topics
- Animals
- Antibodies, Monoclonal
- Antiviral Agents
- Binding Sites
- CD4 Antigens
- CD4 Immunoadhesins
- Cell Line
- Giant Cells
- HIV Core Protein p24
- HIV Envelope Protein gp120
- HIV-1
- Mutation
- Phenotype
- Recombinant Proteins
- Viral Plaque Assay