Article
Specific uptake of retinol-binding protein by variant F9 cell lines.
The Journal of biological chemistry - 5 Sept 1993
Matarese V, Lodish H F
Abstract excerpt
Serum retinol-binding protein (RBP) specifically binds to and is internalized by F9 embryonal carcinoma cells. Monolayers of F9 cells were differentiated into a primitive endoderm stage by addition of retinoic acid. Fluorescein-derivatized or radiolabeled RBP associated with F9 cell monolayers at 37 degrees C in a time- and concentration-dependent manner. Competition by simultaneous incubation with excess...
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