Article
Partial reversal of transformed fusiform phenotype by overexpression of calreticulin.
Cellular & molecular biology letters - 1 Jan 2007
Opas Michal, Fadel Marc P
Abstract excerpt
Calreticulin, a Ca(2+)-storage and chaperone protein of the ER, has also been shown to affect cell adhesiveness. To examine the effects of differential expression of calreticulin on cellular adhesiveness, we used L fibroblast cell lines stably expressing either elevated or reduced amounts of full length, ER-targeted calreticulin. Overexpression of calreticulin correlates with an increase in adhesiveness of L...
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