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Article

Intracytoplasmic growth and virulence of Listeria monocytogenes auxotrophic mutants.

Infection and immunity - 1 Sept 1993

Marquis H, Bouwer H G, Hinrichs D J, Portnoy D A

Abstract excerpt

The intracellular growth of several auxotrophic mutants of Listeria monocytogenes was examined in cell culture, and virulence was evaluated in mice by intravenous injection of log-phase bacteria. L. monocytogenes transposon insertion mutants requiring either uracil, phenylalanine, glycine, prolin...

Topics

Animals
Cell Line
Cytoplasm
Epithelium
Humans
Lethal Dose 50
Listeria monocytogenes
Macrophages
Mice
Mice, Inbred BALB C
Mutation
Threonine
Virulence

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Identifiers

PMID: 8359896
DOI: 10.1128/iai.61.9.3756-3760.1993
PMCID: PMC281074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8359896-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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