Article
Caenorhabditis elegans is a model host for Listeria monocytogenes.
Applied and environmental microbiology - 1 Feb 2006
Thomsen Line E, Slutz Sandra S, Tan Man-Wah, Ingmer Hanne
Abstract excerpt
Here we report that Caenorhabditis elegans nematodes fed Listeria monocytogenes die over the course of several days, as a consequence of an accumulation of bacteria in the worm intestine. Mutant strains previously shown to be important for virulence in mammalian models were also found to be attenuated in their virulence in C. elegans. However, ActA, which is required for actin-based intracellular motility,...
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