Article
Genetic and molecular analysis of recessive alleles at the pink-eyed dilution (p) locus of the mouse.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1992
Lyon M F, King T R, Gondo Y, Gardner J M, Nakatsu Y, Eicher E M, Brilliant M H
Abstract excerpt
Recessive mutant alleles at the pink-eyed dilution (p) locus on mouse chromosome 7 reduce pigmentation of both the coat and eyes. Here we describe the properties and complementation interactions of 10 p alleles, including 6 not previously reported. Several alleles that cause additional phenotypes affecting development, reproduction, and behavior were shown to be deletions by using DNA probes derived from the p...
Topics
- Alleles
- Animals
- Blotting, Southern
- Chromosome Deletion
- Crosses, Genetic
- DNA
- Eye Color
- Female
- Genes, Recessive
- Genotype
- Male